Hideyuki Takeuchi Selected Research

Dowling-Degos Disease

1/2018	Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features.
1/2016	Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations.

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Hideyuki Takeuchi Research Topics

Disease

17	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021 - 01/2002
17	Multiple Sclerosis 01/2021 - 04/2006
13	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 02/2005
12	Neoplasms (Cancer) 03/2022 - 11/2015
11	Alzheimer Disease (Alzheimer's Disease) 01/2019 - 07/2006
8	Inflammation (Inflammations) 02/2018 - 02/2005
6	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 02/2008
6	Neuroinflammatory Diseases 02/2018 - 12/2012
5	Stomach Neoplasms (Stomach Cancer) 04/2021 - 01/2020
5	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2016 - 12/2007
5	Carcinoma (Carcinomatosis) 08/2012 - 10/2007
4	Nervous System Diseases (Neurological Disorders) 02/2018 - 11/2006
3	Ileus 01/2021 - 03/2020
3	Colorectal Neoplasms (Colorectal Cancer) 08/2020 - 01/2009
2	COVID-19 06/2022 - 01/2021
2	Hemorrhage 04/2022 - 01/2019
2	Stroke (Strokes) 10/2021 - 01/2014
2	Neoplasm Metastasis (Metastasis) 01/2021 - 02/2010
2	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 01/2021 - 10/2019
2	Disease Progression 01/2021 - 01/2011
2	Parkinson Disease (Parkinson's Disease) 01/2021 - 07/2006
2	Pathologic Constriction (Stenosis) 07/2020 - 03/2020
2	Rheumatoid Arthritis 01/2020 - 03/2012
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2018 - 05/2011
2	Dowling-Degos Disease 01/2018 - 01/2016
2	Cognitive Dysfunction 03/2016 - 07/2014
2	Brain Injuries (Brain Injury) 02/2016 - 11/2008
2	Brain Diseases (Brain Disorder) 05/2008 - 02/2005
1	Ataxia (Dyssynergia) 06/2022
1	Guillain-Barre Syndrome 06/2022
1	Dysgeusia (Parageusia) 06/2022
1	Ischemic Stroke 10/2021
1	Venous Thromboembolism 10/2021
1	Lymphoma (Lymphomas) 04/2021
1	Adenocarcinoma 02/2021
1	Multiple System Atrophy 01/2021
1	Apraxias (Dyspraxia) 01/2021
1	Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy) 01/2021

Drug/Important Bio-Agent (IBA)

11	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2002
10	Glutamic Acid (Glutamate)FDA Link 01/2017 - 07/2006
8	CytokinesIBA 01/2018 - 02/2005
6	Superoxide Dismutase-1IBA 10/2016 - 08/2002
5	Amyloid (Amyloid Fibrils)IBA 01/2019 - 01/2011
4	Polysaccharides (Glycans)IBA 01/2020 - 10/2007
4	Fingolimod Hydrochloride (FTY720)FDA Link 01/2019 - 01/2013
4	LipopolysaccharidesIBA 02/2018 - 01/2016
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2009 - 07/2006
4	Interferon-gamma (Interferon, gamma)IBA 11/2009 - 04/2006
3	Messenger RNA (mRNA)IBA 06/2022 - 03/2008
3	Heparin (Liquaemin)FDA LinkGeneric 10/2021 - 03/2008
3	Pharmaceutical PreparationsIBA 01/2021 - 01/2013
3	Sphingosine-1-Phosphate ReceptorsIBA 01/2019 - 01/2013
3	EnzymesIBA 11/2016 - 11/2015
3	MidkineIBA 02/2014 - 03/2008
3	Glutamate Receptors (Glutamate Receptor)IBA 01/2014 - 07/2006
3	InterleukinsIBA 05/2008 - 02/2008
2	LigandsIBA 02/2021 - 11/2009
2	Myelin-Oligodendrocyte GlycoproteinIBA 01/2021 - 12/2007
2	Dimethyl FumarateIBA 01/2021 - 01/2019
2	Pemetrexed (MTA)FDA Link 12/2020 - 01/2018
2	Biomarkers (Surrogate Marker)IBA 11/2020 - 02/2018
2	Immunoglobulin G (IgG)IBA 01/2020 - 03/2012
2	Indocyanine Green (Cardio-Green)FDA LinkGeneric 01/2020 - 01/2020
2	INI-0602IBA 01/2018 - 12/2014
2	ConnexinsIBA 01/2018 - 01/2014
2	3,3'-iminodipropionitrileIBA 08/2017 - 01/2016
2	CaspasesIBA 10/2016 - 12/2002
2	Immunosuppressive Agents (Immunosuppressants)IBA 01/2016 - 07/2014
2	Conditioned Culture MediaIBA 01/2016 - 10/2015
2	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 03/2013 - 01/2013
2	Phosphates (Orthophosphate)IBA 03/2013 - 01/2013
2	Nucleotide AptamersIBA 03/2012 - 03/2008
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2012 - 03/2008
2	Interleukin-17 (Interleukin 17)IBA 11/2009 - 02/2008
1	BNT162 VaccineIBA 06/2022
1	COVID-19 VaccinesIBA 06/2022
1	VaccinesIBA 06/2022
1	LipidsIBA 04/2022
1	Notch ReceptorsIBA 03/2022
1	AnticoagulantsIBA 10/2021
1	fibrin fragment D (D-dimer)IBA 10/2021
1	Factor Xa InhibitorsIBA 10/2021
1	Rituximab (Mabthera)FDA Link 04/2021
1	Prednisone (Sone)FDA LinkGeneric 04/2021
1	Vincristine (Oncovin)FDA LinkGeneric 04/2021
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 04/2021
1	polyglutamineIBA 01/2021
1	Glutamine (L-Glutamine)FDA Link 01/2021
1	AntibodiesIBA 01/2021
1	Sodium Glutamate (Accent)IBA 01/2021

Therapy/Procedure

6	Therapeutics 10/2021 - 05/2011
5	Gastrectomy 04/2021 - 01/2020
3	Lymph Node Excision (Lymph Node Dissection) 01/2021 - 01/2020
3	Surgical Instruments (Clip) 08/2020 - 01/2019
2	Drug Therapy (Chemotherapy) 04/2021 - 12/2020
2	Laparoscopes (Laparoscope) 01/2020 - 01/2020
2	Renal Dialysis (Hemodialysis) 01/2019 - 01/2018
1	Laparoscopic Cholecystectomy 04/2021
1	Decompression 01/2021
1	Immunotherapy 01/2021